A novel combination of an IgE mediated adult onset food allergy and a suspected mast cell activation syndrome presenting as anaphylaxis / دانلود فایل

مشخصات کلی A novel combination of an IgE mediated adult onset food allergy and a suspected mast cell activation syndrome presenting as anaphylaxis

نویسنده کتاب (Author):

Barber, Colin; Kalicinsky, Chrystyna

انتشارات (Publisher):

BioMed Central Ltd. 2016-09-17

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

BioMed Central Ltd.

موضوع (Subject):

Adult onset food allergy, Mast cell activation syndrome, Anaphylaxis      

توضیحات خلاصه (Summary):

Abstract Background Adult onset food allergy is a rare, but increasingly recognized phenomenon. Mast cell activation syndromes present an ongoing diagnostic and classification challenge. The combination of the two has been rarely described in the literature. Case presentation We present a case of a new onset, IgE mediated food allergy in combination with a mast cell activation syndrome in an elderly patient not known to have a history of atopy. He presented to a hospital with a first presentation of anaphylaxis manifesting profound hypotension following consumption of a stew consisting of fish and shellfish. He had a persistently elevated serum tryptase and demonstrated evidence of high titre serum specific IgE to shellfish. He responded well to histaminergic blockade. Conclusions Given that mast cell activation syndromes pose an increased risk for recurrent, severe anaphylaxis and that secondary causes of mast cell activation syndromes are more prevalent with aging, this case highlights the importance of considering this entity when evaluating an elderly patient with a first presentation of anaphylaxis.  Read more…

ژانر / فرم:Case Report

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Barber, Colin; Kalicinsky, Chrystyna

شناسه OCLC:979265185

Language Note:English

Anaphylaxis to supplemental oral lactase enzyme / دانلود فایل

مشخصات کلی Anaphylaxis to supplemental oral lactase enzyme

نویسنده کتاب (Author):

Voisin, M.; Borici-Mazi, R.

انتشارات (Publisher):

BioMed Central Ltd. 2016-12-13

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

BioMed Central Ltd.

موضوع (Subject):

Anaphylaxis, Lactase allergy, Aspergillus, Lactose intolerance, IgE mediated      

توضیحات خلاصه (Summary):

Abstract Background Anaphylactic reactions involving IgE mediated hypersensitivity have been frequently reported for a number of uncommon foods. However, cases of anaphylaxis to over the counter vitamins and oral supplements have been rarely published. Lactose intolerance affects approximately 20% of Canadians and roughly 70% of the world’s population of any age. Lactose intolerance develops primarily due to the absence of the enzyme lactase and treatment involves avoidance of lactose-containing foods or ingestion of commercially available lactase enzyme preparations prior to their consumption. This case report represents the first documented evidence of anaphylaxis after exposure to supplemental lactase enzyme preparation. Case presentation A 38 years old Caucasian female presented with a history of self-diagnosed adult-onset lactose intolerance and a suspected allergy to lactase containing tablets. She reported an episode of bilateral orbital swelling, shortness of breath, and throat constriction after oral ingestion of a supplemental lactase enzyme tablet. Her symptoms slowly resolved with the administration of inhaled salbutamol and oral diphenhydramine. She handled lactase tablets for years to her children who were lactose intolerant, but had never ingested the tablets herself prior to the reported episode. In clinic, physical examination was benign, and skin prick testing to a slurry of the lactase tablet revealed a strongly positive reaction wheal size of 10 mm and flare of 60 mm with normal controls. The patient reported throat tightness and constriction after skin prick testing and required cetirizine treatment and observation in clinic. Subsequent skin testing was performed with individual ingredients of the lactase tablet provided by the manufacturer and Aspergillus niger , a common bacteria used in lactase preparations. Only concentrated lactase enzyme elicited a positive response. The patient was diagnosed with lactase tablet induced anaphylaxis due to  Read more…

ژانر / فرم:Case report

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Voisin, M.; Borici-Mazi, R.

شناسه OCLC:979265181

Language Note:English

Hereditary angioedema: health-related quality of life in Canadian patients as measured by the SF-36 / دانلود فایل

مشخصات کلی Hereditary angioedema: health-related quality of life in Canadian patients as measured by the SF-36

نویسنده کتاب (Author):

Jindal, Nina; Harniman, Elaine; Prior, Nieves; Perez-Fernandez, Elia; Caballero, Teresa; Betschel, Stephen

انتشارات (Publisher):

BioMed Central Ltd. 2017-01-19

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

BioMed Central Ltd.

موضوع (Subject):

Hereditary angioedema, HAE, Quality of Life, SF-36, C1-inhibitor      

توضیحات خلاصه (Summary):

Abstract Background Hereditary angioedema (HAE) is a rare but serious condition characterized by recurrent spontaneous attacks of angioedema affecting superficial tissues of upper respiratory and gastrointestinal tracts. The potentially fatal and disfiguring nature of HAE impacts the health-related quality of life (HRQoL) of patients with this condition. Objectives To assess the health-related quality of life of Canadian patients with HAE using the 36-item Short-Form Health Survey (SF-36v2). Methods Twenty-one patients living in Canada over age 18 with known diagnosis of hereditary angioedema due to C1-INH deficiency (HAE), completed the SF-36v2 (generic HRQoL questionnaire). Results were compared to Canadian normative data by converting the SF-36 scores into z scores. Results The SF-36v2 showed a significant reduction in general health (p = 0.0063) in patients with HAE when compared with healthy Canadians. Percentage of patients with z scores below 0.8 (large effect) was 47.6% for general health subscale, 33.3% for bodily pain and vitality subscales and 28.6% for physical component scores. Mean scores of eight dimensions ranged from 57.7 to 88.9. Mean Physical and mental component scores were 49.1 and 50.4. Internal consistency of evaluation was demonstrated by Cronbach’s alpha value above 0.7 for all scales. General perception of health was significantly different in these patients, compared to Canadian normative data. Conclusions This study of Canadian patients with HAE shows that General Health is most frequently affected followed by Bodily Pain and Vitality, as measured by SF-36v2. The SF-36v2 offers valuable insight to assess quality of life in patients with HAE, however a larger number of Canadian patients and specific tools for assessment are needed for better evaluation.  Read more…

ژانر / فرم:Short report

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Jindal, Nina; Harniman, Elaine; Prior, Nieves; Perez-Fernandez, Elia; Caballero, Teresa; Betschel, Stephen

شناسه OCLC:979265179

Language Note:English

Polyethylene glycol as a cause of anaphylaxis / دانلود فایل

مشخصات کلی Polyethylene glycol as a cause of anaphylaxis

نویسنده کتاب (Author):

Wylon, Katharina; Dölle, Sabine; Worm, Margitta

انتشارات (Publisher):

BioMed Central Ltd. 2016-12-13

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

BioMed Central Ltd.

موضوع (Subject):

Anaphylaxis, Drug additives, Hypersensitivity, Macrogol, Polyethylene glycol      

توضیحات خلاصه (Summary):

Abstract Background Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. Case report We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick tests, intradermal tests (IDT) and a double-blind oral challenge was performed to identify the trigger of anaphylaxis. In the present case hypersensitivity to the additive polyethylene glycol was confirmed by an IDT suggesting an Immunoglobulin E-dependent mechanism as a cause of the reaction. Conclusion Potential life-threatening hypersensitivity reactions to hidden molecules like macrogol may be underdiagnosed. Cases of immediate-type PEG hypersensitivity were reported with increasing frequency. The awareness regarding the allergenic potential of PEG should be raised and a proper product labelling is crucial to prevent PEG mediated hypersensitivity.  Read more…

ژانر / فرم:Case report

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Wylon, Katharina; Dölle, Sabine; Worm, Margitta

شناسه OCLC:979265178

Language Note:English

Atopic keratoconjunctivitis complicated by Kocuria koreensis keratitis: the first case / دانلود فایل

مشخصات کلی Atopic keratoconjunctivitis complicated by Kocuria koreensis keratitis: the first case

نویسنده کتاب (Author):

Inada, Noriko; Shoji, Jun; Yamagami, Satoru

انتشارات (Publisher):

BioMed Central Ltd. 2017-01-25

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

BioMed Central Ltd.

موضوع (Subject):

Atopic dermatitis, Atopic keratoconjunctivitis, Kocuria keratitis, Shield ulcer      

توضیحات خلاصه (Summary):

Abstract Background Patients with atopic dermatitis have a predisposition to Staphylococcus aureus and a Herpes simplex virus infection. The treatment of atopic diseases with steroid and immunosuppressive agents induces opportunistic infection. However, there is a concern regarding visual prognosis in patients with atopic keratoconjunctivitis (AKC) complicated with infectious keratitis. We report an unusual case of an atopic shield ulcer with Kocuria keratitis. Case presentation A 51-year-old Japanese man presented with a 14-day history of eye pain and visual loss in his left eye. At the initial examination, a shield ulcer was observed in the upper-central cornea of the left eye, and the conjunctiva in both eyes had a velvety appearance due to papillary formation, as well as hyperemia and swelling in the palpebral area. The shield ulcer showed white stromal opacification in the marginal zone with a coral-like appearance. Samples were obtained by corneal scraping, and Kocuria sp. was identified by microbiological examination including culture and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. The 16S rRNA gene sequence analysis was performed using isolated Kocuria strain from the patient. The obtained DNA sequence showed 99% homology with Kocuria koreensis. The combination of corneal scraping and instillation of cefmenoxime antibiotic ophthalmic solution was considered useful for the treatment of Kocuria keratitis. Conclusion Clinicians should be aware of Kocuria keratitis as a corneal complication of AKC, and that rapid diagnosis of Kocuria keratitis may improve visual prognosis.  Read more…

ژانر / فرم:Case report

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Inada, Noriko; Shoji, Jun; Yamagami, Satoru

شناسه OCLC:979265177

Language Note:English

An avoidable cause of thymoglobulin anaphylaxis / دانلود فایل

مشخصات کلی An avoidable cause of thymoglobulin anaphylaxis

نویسنده کتاب (Author):

Brabant, S.; Facon, A.; Provôt, F.; Labalette, M.; Wallaert, B.; Chenivesse, C.

انتشارات (Publisher):

BioMed Central Ltd. 2017-02-23

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

BioMed Central Ltd.

موضوع (Subject):

Thymoglobulin, Anaphylactic allergic reaction, Rabbit proteins      

توضیحات خلاصه (Summary):

Abstract Background Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injection of thymoglobulin are rare. Case presentation We report a case of serious anaphylactic reaction occurring after a first intraoperative injection of thymoglobulin during renal transplantation in a patient with undiagnosed respiratory allergy to rabbit allergens. Conclusions This case report reinforces the importance of identifying rabbit allergy by a simple combination of clinical interview followed by confirmatory skin testing or blood tests of all patients prior to injection of thymoglobulin, which is formally contraindicated in patients with a history of hypersensitivity to rabbit proteins.  Read more…

ژانر / فرم:Case Report

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Brabant, S.; Facon, A.; Provôt, F.; Labalette, M.; Wallaert, B.; Chenivesse, C.

شناسه OCLC:979265171

Language Note:English